Sama Aghababayan, Zahra Sheikhi Mobarakeh, Mostafa Qorbani, Fereshteh Abbasvandi, Zeinab Tiznobeyk, Azadeh Aminianfar, Gity Sotoudeh
Nutrition and cancer 2020Background: Dietary phytochemical index (DPI) is an inexpensive method for estimating the amounts of phytochemicals in foods. No study has investigated the association of DPI and benign breast diseases (BBD). Our study aimed to compare DPI in patients with BBD and the control group.Subjects: This is a case-control study of 115 subjects with BBD and 116 healthy women attending the Iranian Center for Breast Cancer affiliated with Academic Center for Education, Culture and Research. Energy-adjusted DPI was calculated based on data collected from 168-item validated food frequency questionnaire. Sociodemographic data, physical activity, and anthropometric measures such as body weight, height, and waist circumference were determined.Results: After adjustment for age, estrogen therapy, family history of breast disease, intake of dietary supplement, menopause status, waist circumference and physical activity, the odds ratio (OR) of BBD across the energy-adjusted DPI quartiles decreased significantly (OR = 0.3, 95%CI = 0.12-0.93) (P‑trend = 0.02).Conclusion: We found that higher DPI score is related to lower BBD OR. This simple method may be used for the improvement of dietary intake to prevent BBD.
Sama Aghababayan, Zahra Sheikhi Mobarakeh, Mostafa Qorbani, Fereshteh Abbasvandi, Zeinab Tiznobeyk, Azadeh Aminianfar, Gity Sotoudeh. Dietary Phytochemical Index and Benign Breast Diseases: A Case-Control Study. Nutrition and cancer. 2020;72(6):1067-1073
PMID: 31475586
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