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Isolation and structure determination of new chymotrypsin inhibitory peptides streptopeptolins B and C.
Ankit Tiwari, Issara Kaweewan, Yuto Miyake, Hikaru Hemmi, Shinya Kodani
Natural product research 2021 AugSizes of these terms reflect their relevance to your search.
New chymotrypsin inhibitory peptides named streptopeptolins B and C were isolated from Streptomyces olivochromogenes. Structures of streptopeptolins B and C were determined to be cyclic depsipeptides possessing 3-amino-6-hydroxy-2-piperidone unit by interpretation of NMR spectra and ESI-MS. Streptopeptolins B and C showed inhibitory activities to chymotrypsin with IC50 of 8.0 and 12.0 μg/mL, respectively.
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Ankit Tiwari, Issara Kaweewan, Yuto Miyake, Hikaru Hemmi, Shinya Kodani. Isolation and structure determination of new chymotrypsin inhibitory peptides streptopeptolins B and C. Natural product research. 2021 Aug;35(16):2700-2706
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PMID: 31512511
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