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The process of entry into a host cell is a key step in the life cycle of most viruses. In recent years, there has been a significant increase in our understanding of the routes and mechanisms of entry for a number of these viruses. This has led to the development of novel broad-spectrum antiviral approaches that target host cell proteins and pathways, in addition to strategies focused on individual viruses or virus families. Here we consider a number of these approaches and their broad-spectrum potential.

Citation

Michela Mazzon, Mark Marsh. Targeting viral entry as a strategy for broad-spectrum antivirals. F1000Research. 2019;8

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PMID: 31559009

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