Pneumonitis Due to Oren-gedoku-to (Coptis Detoxifying Decoction).

A 54-year-old man started to take oren-gedoku-to (coptis detoxifying decoction) because he was experiencing chronic hot flashes, night sweats and insomnia. He developed a high fever from the day of intake. At day 17, he stopped taking oren-gedoku-to because of malaise and chills, and he was admitted to our hospital. Drug-induced pneumonitis was suspected, and all drugs were stopped. Consequently, his symptoms, laboratory data and chest X-ray findings markedly improved. The results of a lymphocyte stimulation test were positive for oren-gedoku-to and one of its components, ougon (Baikal skullcap). Based on these findings, we diagnosed him with pneumonitis caused by ougon.

Citation

Naoto Mochizuki, Satoshi Ano, Norihiro Kikuchi, Chio Sakai, Michiko Masuda, Yuzuru Kondo, Yukio Ishii. Pneumonitis Due to Oren-gedoku-to (Coptis Detoxifying Decoction). Internal medicine (Tokyo, Japan). 2019;58(20):3019-3023

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PMID: 31611510

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