Pediatric Kaposi's sarcoma associated with immune reconstitution inflammatory syndrome.

Leandro Silva, Laura Azurara, Ana Filipe Monteiro, Alexandre Miroux-Catarino, Cristina Amaro, Isabel Viana

Pediatric dermatology 2020 Jan

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Immune reconstitution inflammatory syndrome (IRIS) represents paradoxical immune-mediated inflammation in response to an infecting pathogen, occurring after initiation of antiretroviral therapy (ART), concomitantly with immune system recovery. It has also been described in Kaposi's sarcoma (KS). We report a case of a 9-year-old Guinean girl, who developed Kaposi's sarcoma, following introduction of ART. KS associated with immune reconstitution inflammatory syndrome is rare, especially in children, but with the increased use of ART is becoming more prevalent. © 2019 Wiley Periodicals, Inc.

Citation

Leandro Silva, Laura Azurara, Ana Filipe Monteiro, Alexandre Miroux-Catarino, Cristina Amaro, Isabel Viana. Pediatric Kaposi's sarcoma associated with immune reconstitution inflammatory syndrome. Pediatric dermatology. 2020 Jan;37(1):239-240