SimRVSequences: an R package to simulate genetic sequence data for pedigrees.

We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample of unrelated individuals. SimRVSequences is publicly-available on CRAN https://cran.r-project.org/web/packages/SimRVSequences/. Supplementary data are available at Bioinformatics online. © The Author(s) 2019. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Citation

Christina Nieuwoudt, Angela Brooks-Wilson, Jinko Graham. SimRVSequences: an R package to simulate genetic sequence data for pedigrees. Bioinformatics (Oxford, England). 2020 Apr 01;36(7):2295-2297

Mesh Tags

PMID: 31764964

search → result