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Diagnosis of acanthamoeba keratitis is often a clinical challenge. In most cases it is primarily confused with herpes keratitis. A coinfection with bacteria or fungi can also lead to a delayed diagnosis and initiation of treatment. A few cases reported the detection of acanthamoeba in the anterior chamber. In the case of endophthalmitis without the detection of bacteria or fungi acanthamoeba should therefore always be considered as a potential differential diagnosis. The local and systemic administration of voriconazole can be successfully used to treat acanthamoeba endophthalmitis.

Citation

J Pascha, A Frings, J Walochnik, E Wissiak, M Dirisamer, L Daas, N Ardjomand. Acanthamoeba endophthalmitis-a case report]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 2020 Sep;117(9):926-929

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PMID: 31768616

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