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In the wake of the Children's Oncology Group (COG) ANBL00P2 trial and the ongoing ANBL1232 trial, an increasing number of children with neonatal neuroblastoma are being managed nonoperatively. We report the case of a patient with low-risk, non-MYCN amplified, neuroblastoma that was diagnosed and resected in the neonatal period but subsequently developed pulmonary metastases by the age of 7 months. Though rare, the possibility of low-risk disease metastasizing during surveillance should be recognized and may not be identified by current protocols. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.


Sarah J Ullrich, David Worhunsky, Rozalyn Rodwin, Farzana Pashankar, Emily Christison-Lagay, Doruk Ozgediz. Pulmonary Metastasis of Low-risk Perinatal Neuroblastoma After Resection: Implications for Surveillance. Journal of pediatric hematology/oncology. 2021 Mar 01;43(2):e184-e186

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PMID: 31815890

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