The Effect of Body Composition and Energy Expenditure on Permethrin Biomarker Concentrations Among US Army National Guard Members.

To examine relationships between percent body fat (%BF) and total energy expenditure (TEE) on permethrin exposure among Army National Guard (ARNG) Soldiers wearing permethrin-treated uniforms. ARNG members (n = 47) participated in a 9-day study. Repeated body composition (height, weight, %BF) measurements and daily urine samples, analyzed for permethrin and N,N-diethyl-meta-toluamide (DEET) metabolites, were collected. TEE was determined via doubly labeled water protocol. Linear mixed and regression models were used for analyses. Neither %BF nor TEE were significantly associated with permethrin or DEET biomarkers. However, a significant interaction effect (F = 10.76; P = 0.0027) between laundering history and %BF was observed; 10% higher %BF was significantly associated with 25% higher permethrin biomarker concentrations among those wearing uniforms washed less than or equal to 25 (compared with more than 25) times. Uniform laundering history significantly affects the association between %BF and permethrin-treated uniform exposure.

Citation

Matthew M Scarpaci, Caitlin C Haven, Alexis L Maule, Kristin J Heaton, Kathryn M Taylor, Jennifer Rood, Maria Ospina, Antonia M Calafat, Susan P Proctor. The Effect of Body Composition and Energy Expenditure on Permethrin Biomarker Concentrations Among US Army National Guard Members. Journal of occupational and environmental medicine. 2020 Mar;62(3):210-216

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PMID: 31895734

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