Meroterpenoid pyrones, alkaloid and bicyclic brasiliamide from the fungus Neosartorya hiratsukae.

Jakkapat Paluka, Kwanjai Kanokmedhakul, Mayamor Soytong, Kasem Soytong, Jantana Yahuafai, Pongpun Siripong, Somdej Kanokmedhakul

Fitoterapia 2020 Apr

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Two new meroterpenoid pyrones, chevalone G (1) and aszonapyrone C (2), a new indole alkaloid, 7-chlorofischerindoline (3) and a new bicyclic brasiliamide, brasiliamide H (4), together with sixteen known compounds, 5-20 were isolated from the fungus Neosartorya hiratsukae. Their structures were established on the basis of spectroscopic evidence. The antibacterial activity and the cytotoxic activity of new compounds were evaluated. Copyright © 2020 Elsevier B.V. All rights reserved.

Citation

Jakkapat Paluka, Kwanjai Kanokmedhakul, Mayamor Soytong, Kasem Soytong, Jantana Yahuafai, Pongpun Siripong, Somdej Kanokmedhakul. Meroterpenoid pyrones, alkaloid and bicyclic brasiliamide from the fungus Neosartorya hiratsukae. Fitoterapia. 2020 Apr;142:104485