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1,2,4-Triazole derivatives possess promising in vitro and in vivo anticancer activity, and many anticancer agents such as fluconazole, tebuconazole, triadimefon, and ribavirin bear a 1,2,4-triazole moiety, revealing their potential in the development of novel anticancer agents. This review emphasizes the recent advances in 1,2,4-triazole-containing compounds with anticancer potential, and the structureactivity relationships as well as mechanisms of action are also discussed. Copyright© Bentham Science Publishers; For any queries, please email at


Xiaoyue Wen, Yongqin Zhou, Junhao Zeng, Xinyue Liu. Recent Development of 1,2,4-triazole-containing Compounds as Anticancer Agents. Current topics in medicinal chemistry. 2020;20(16):1441-1460

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PMID: 31994462

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