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Phosphoinositides (PI) are key players in many trafficking and signaling pathways. Recent advances regarding the synthesis, location and functions of these lipids have improved our understanding of how and when these lipids are generated and what their roles are in physiology and disease. In particular, PI play a central role in the regulation of cell proliferation and metabolism. Here, we will review recent advances in our understanding of PI function, regulation, and importance in different aspects of proliferation and energy metabolism. Copyright © 2020 Elsevier Ltd. All rights reserved.


Emilio Hirsch, Federico Gulluni, Miriam Martini. Phosphoinositides in cell proliferation and metabolism. Advances in biological regulation. 2020 Jan;75:100693

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PMID: 32008962

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