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    The relationship between preexisting osteoarthritic pain and subsequent post-total knee arthroplasty (TKA) pain is not well defined. This knowledge gap makes diagnosis of post-TKA pain and development of management plans difficult and may impair future investigations on personalized care. Therefore, a set of diagnostic criteria for identification of acute post-TKA pain would inform standardized management and facilitate future research. The Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership with the US Food and Drug Administration (FDA), the American Pain Society (APS), and the American Academy of Pain Medicine (AAPM) formed the ACTTION-APS-AAPM Pain Taxonomy (AAAPT) initiative to address this goal. A multidisciplinary work group of pain experts was invited to conceive diagnostic criteria and dimensions of acute post-TKA pain. The working group used contemporary literature combined with expert opinion to generate a five-dimensional taxonomical structure based upon the AAAPT framework (i.e., core diagnostic criteria, common features, modulating factors, impact/functional consequences, and putative mechanisms) that characterizes acute post-TKA pain. The diagnostic criteria created are proposed to define the nature of acute pain observed in patients following TKA. © 2020 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail:


    Faraj W Abdallah, Ian Gilron, Roger B Fillingim, Patrick Tighe, Hari K Parvataneni, Nader Ghasemlou, Mona Sawhney, Colin J L McCartney. AAAPT Diagnostic Criteria for Acute Knee Arthroplasty Pain. Pain medicine (Malden, Mass.). 2020 May 01;21(5):1049-1060

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    PMID: 32022891

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