Sylwia Stączek, Agnieszka Zdybicka-Barabas, Małgorzata Pleszczyńska, Adrian Wiater, Małgorzata Cytryńska
Journal of invertebrate pathology 2020 MarPhenoloxidase (PO) is a key enzyme in the melanization process involved in elimination of pathogens in insects. The PO system is rapidly activated in response to pathogen recognition. Inhibition of PO activity can be a way to avoid immune response and increase infection effectiveness. In this study, the effects of inoculation of Galleria mellonella larvae with Aspergillus niger α-1,3-glucan and conidia on PO activity in hemolymph are analyzed in comparison with the effects of β-1,3/1,6-glucan inoculation. Our results indicate that α-1,3-glucan, a fungal cell wall polysaccharide, can play a role of a virulence factor involved in inhibition of the insect PO system. Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
Sylwia Stączek, Agnieszka Zdybicka-Barabas, Małgorzata Pleszczyńska, Adrian Wiater, Małgorzata Cytryńska. Aspergillus niger α-1,3-glucan acts as a virulence factor by inhibiting the insect phenoloxidase system. Journal of invertebrate pathology. 2020 Mar;171:107341
PMID: 32057750
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