Effects of insecticide resistance and exposure on Plasmodium development in Anopheles mosquitoes.

The spread of insecticide resistance in anopheline mosquitoes is a serious threat to the success of malaria control and prospects of elimination, but the potential impact(s) of insecticide resistance or sublethal insecticide exposure on Plasmodium-Anopheles interactions are poorly understood. Only a few studies have attempted to investigate such interactions, despite their clear epidemiological significance for malaria transmission. This short review provides an update on our understanding of the interactions between insecticide resistance and exposure and Plasmodium development, focusing on the mechanisms which might underpin any interactions, and identifying some key knowledge gaps. Copyright © 2020 Elsevier Inc. All rights reserved.

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Corrado Minetti, Victoria A Ingham, Hilary Ranson. Effects of insecticide resistance and exposure on Plasmodium development in Anopheles mosquitoes. Current opinion in insect science. 2020 Jun;39:42-49

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PMID: 32109860

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