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Although mucociliary clearance is important for preventing pneumonia, its association with the onset of pneumonia is unclear. The aim of this study is to examine the association between saccharin test results as a potential measure of mucociliary clearance and history of pneumonia in nursing home residents. Ninety elderly nursing home residents (elderly group) were selected, 35 of whom had a history of pneumonia. Twenty-five healthy adults (adult group) were also investigated to provide baseline values for this study. We conducted the saccharin test to evaluate mucociliary clearance and compared the saccharin time (ST) between those with and without history of pneumonia. Mean ST in the adult group was 12±6 min. The ST in the pneumonia group was significantly longer than that in the non-pneumonia group (32±23 min vs. 17±13 min) (p<0.05). Impaired mucociliary clearance is a factor in the development of pneumonia among nursing home residents. Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.


Yurika Uchida, Kanji Nohara, Nobukazu Tanaka, Nami Fujii, Hikari Fukatsu, Nobuko Kaneko, Makoto Mitsuyama, Takayoshi Sakai. Comparison of Saccharin Time in Nursing Home Residents With and Without Pneumonia: A Preliminary Study. In vivo (Athens, Greece). 2020 Mar-Apr;34(2):845-848

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PMID: 32111793

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