Photorefractive intrastromal crosslinking for correction of hyperopia: 12-month results.

To evaluate the efficacy of epithelium-on photorefractive intrastromal crosslinking (PiXL), a noninvasive procedure to reduce refractive error in patients with low hyperopia. Gemini Eye Clinic, Zlin, Czech Republic. Prospective single-center study. Twenty-two low hyperopic eyes were enrolled and underwent PiXL treatment according to a standardized treatment protocol. Visual acuity, subjective distance refraction, keratometry, topography, pachymetry, subjective discomfort, and endothelial cell density (ECD) were recorded during 12-month follow-up. In 22 eyes, the median manifest refraction decreased significantly (P < .0001) from +0.75 diopters (D) (interquartile range [IQR], +0.63 to +1.06 D), median and IQR) diopters (D) preoperatively to +0.25 D (IQR, 0.0 to +0.50 D) at 12-month follow-up and remained stable. Seventy-seven percent of eyes achieved refraction within ± 0.50 D of emmetropia by 1 month postoperatively and was stable through 12-month follow-up. ECD was stable and did not show significant changes. There was low incidence of postoperative pain and dry eye. PiXL is a promising alternative to conventional laser refractive surgeries for low hyperopia. Further studies are warranted to optimize treatment parameters for a wider range of refractive errors and to evaluate the potential to improve precision.

Citation

Pavel Stodulka, Zuzana Halasova, Martin Slovak, Martin Sramka, Karel Liska, Jaroslav Polisensky. Photorefractive intrastromal crosslinking for correction of hyperopia: 12-month results. Journal of cataract and refractive surgery. 2020 Mar;46(3):434-440

Mesh Tags

Substances

PMID: 32142499

search → result