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Nucleoporin Condensates Drive Nuclear Pore Complex Assembly in Oocytes.

George W Mobbs, André Hoelz

Trends in biochemical sciences 2020 Apr


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    Oocytes stockpile nuclear pore complexes (NPCs) in cytoplasmic membrane sheets called annulate lamellae (AL) in preparation for rapid cell cycles during embryogenesis. Recently, Hampoelz et al. reported that AL-NPC assembly depends on the coordinated formation, transport, and interaction of biomolecular condensates containing distinct sets of nucleoporins. Copyright © 2020. Published by Elsevier Ltd.

    Citation

    George W Mobbs, André Hoelz. Nucleoporin Condensates Drive Nuclear Pore Complex Assembly in Oocytes. Trends in biochemical sciences. 2020 Apr;45(4):278-280

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    PMID: 32169173

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