Evaluation of the susceptibility test of polymyxin B using the commercial test Policimbac®.

Broth microdilution (BMD), the reference method to determine bacterial susceptibility to polymyxins, is a laborious and time-consuming technique. Policimbac® is a commercial test panel which uses lyophilized polymyxin B to determine the minimum inhibitory concentration for Gram-negative isolates. This study evaluated the performance of Policimbac® in comparison with BMD for 110 isolates. Although the Policimbac® presented a very low essential agreement, the categorical agreement with BMD was optimal. Policimbac® is an alternative approach to BMD for evaluating the susceptibility to polymyxin B.

Citation

Tanise Vendruscolo Dalmolin, Maiara Dos Santos Carneiro, Luíza Peres de Castro, Fabiana Caroline Zempulski Volpato, Priscila Lamb Wink, Daiana de Lima-Morales, Afonso Luís Barth. Evaluation of the susceptibility test of polymyxin B using the commercial test Policimbac®. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2020 Sep;51(3):1135-1137

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PMID: 32198730

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