Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Sepsis remains medically challenging, with high morbidity and mortality. A novel intervention is urgently needed in the absence of specific, targeted therapy. Neutrophils act as double-edged swords in sepsis; they can help to eradicate microbes, but they also contribute to tissue injury. β2 integrins are critical adhesion molecules that regulate a number of neutrophil functions. β2 integrins consist of four members, namely, αLβ2, αMβ2, αXβ2, and αDβ2. Here, we review the role of each β2 integrin in neutrophils and sepsis and consider future direction for therapeutic intervention. Copyright © 2020 American Society for Microbiology.


Koichi Yuki, Lifei Hou. Role of β2 Integrins in Neutrophils and Sepsis. Infection and immunity. 2020 May 20;88(6)

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 32205406

View Full Text