BaseSpace
Correlation Engine 2.0
Import Your Data
Literature

FAQ

More FAQs

Back to top
Clear Search sequence regions
(e.g. rs2230926, DNMT1, T cell differentiation, Lung cancer, Liver, Nosology, Clofibrate)
Bookmark Forward

Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy.

Nicholas G Paciaroni, John M Ndungu, Thomas Kodadek

Chemical communications (Cambridge, England) 2020 Apr 30


filter terms:
  • aldehyde (4)
  • gene library (3)
  • phase (3)
    • Sizes of these terms reflect their relevance to your search.

    We report chemistry suitable for the solid-phase synthesis of DNA-encoded libraries with an unusually high level of structural diversity. The strategy involves "exploding" an immobilized aldehyde into a plethora of different functional groups under DNA-compatible conditions.

    Citation

    Nicholas G Paciaroni, John M Ndungu, Thomas Kodadek. Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy. Chemical communications (Cambridge, England). 2020 Apr 30;56(34):4656-4659

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 32215395

    View Full Text
    • Copyright © 2024 Illumina Inc. All rights reserved.