GERD: A practical approach.

Andrew Young, Mythri Anil Kumar, Prashanthi N Thota

Cleveland Clinic journal of medicine 2020 Apr

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Gastroesophageal reflux disease (GERD) is mainly a clinical diagnosis based on typical symptoms of heartburn and acid regurgitation. Current guidelines indicate that patients with typical symptoms should first try a proton pump inhibitor (PPI). If reflux symptoms persist after 8 weeks on a PPI, endoscopy of the esophagus is recommended, with biopsies taken to rule out eosinophilic esophagitis. This review discusses the evidence for different medical, endoscopic, and surgical therapies and presents a management algorithm. Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.