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Dental technicians may be chronically exposed to methyl methacrylate (MMA), used in the production of dental prostheses. We have studied whether occupational exposure to MMA affects genotoxicity biomarkers such as 8-OHdG formation, comet assay, and buccal micronucleus frequency. MMA exposure was assessed via ambient air analysis. Although no significant differences between exposed and non-exposed individuals were seen with respect to blood genotoxicity measurements, we found a higher level of buccal-cell anomalies in the exposed group. Copyright © 2020 Elsevier B.V. All rights reserved.


Buğra Soykut, Onur Erdem, Can Özgür Yalçın, Aylin Üstündağ, Yalçın Duydu, Cemal Akay, Bülent Pişkin. Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment. Mutation research. Genetic toxicology and environmental mutagenesis. 2020 Apr;852:503159

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PMID: 32265039

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