A Rare Case of Infertility: SRY Positive 46, XX Testicular Disorder of Sexual Differentiation.

D Bogdanet, T P Griffin, M Bell

Irish medical journal 2020 Apr 03

filter terms:

Aim To highlight the complexity of infertility causes by describing the rare case of a man with a testicular disorder of sexual differentiation. Diagnosis A 33 years old Caucasian male presented with a 3-year-old history of primary infertility. His investigations revealed a low testosterone and a raised LH and FSH levels. A sample sent for sperm analysis revealed azoospermia. Chromosomal analysis and karyotyping revealed a 46 XX SRY positive karyotype. Treatment The patient was initiated on testosterone replacement and on calcium/vitamin D supplements. Conclusion Fertility evaluation requires complex assessments and a broad knowledge of possible causes.

Citation

D Bogdanet, T P Griffin, M Bell. A Rare Case of Infertility: SRY Positive 46, XX Testicular Disorder of Sexual Differentiation. Irish medical journal. 2020 Apr 03(4):60