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Radioligands targeting purinergic P2X7 receptor.
Bioorganic & medicinal chemistry letters 2020 Jun 15Sizes of these terms reflect their relevance to your search.
The purinergic P2X7 receptor (P2X7R) is an adenosine triphosphate (ATP) ligand-gated cationic channel receptor. P2X7R is closely associated with various inflammatory, immune, cancer, neurological, musculoskeletal and cardiovascular disorders. P2X7R is an interesting therapeutic target as well as molecular imaging target. This brief digest highlights the radioligands targeting P2X7R recently developed in drug discovery and molecular imaging agent development. Copyright © 2020 Elsevier Ltd. All rights reserved.
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Qi-Huang Zheng. Radioligands targeting purinergic P2X7 receptor. Bioorganic & medicinal chemistry letters. 2020 Jun 15;30(12):127169
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PMID: 32273217
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