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    We have fabricated an ultrasensitive exosome biosensor based on a multipedal DNA walker with a core of target exosomes. Specific recognition is achieved by introducing a CD63 aptamer and facile separation is obtained with magnetic Fe3O4@Au nanoparticles. A limit of detection down to 6/μL is obtained with excellent selectivity.


    Peng Miao, Yuguo Tang. A multipedal DNA walker for amplified detection of tumor exosomes. Chemical communications (Cambridge, England). 2020 May 07;56(37):4982-4985

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    PMID: 32289816

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