African Horse Sickness Fever in Vaccinated Horses: Short Communication.

Our investigation has shown that multiple vaccinations with inactivated African horse sickness (AHS) vaccines containing all 9 serotypes and produced at the Central Veterinary Research Laboratory in Dubai, UAE, protect horses from AHS. However, the immunization did not prevent African horse sickness fever (AHSF) in approximately 10% of the vaccinated horses despite high enzyme-linked immunosorbent assay and virus neutralizing antibodies. African horse sickness fever is a very mild form of AHS with similar clinical signs. From all 6 horses which had developed AHSF, no virus was isolated from EDTA blood withdrawn during the acute phase of infection. Despite high neutralizing antibodies, serotype 9 was detected by polymerase chain reaction in 4 of them. All 6 horses recovered within 72 hours, after they developed mild clinical signs of AHS. Copyright © 2020 Elsevier Inc. All rights reserved.

Citation

Ulrich Wernery, Sunitha Joseph, Rekha Raghavan, Bimbi Dyer, Sara Spendrup. African Horse Sickness Fever in Vaccinated Horses: Short Communication. Journal of equine veterinary science. 2020 May;88:102967

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PMID: 32303305

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