RETRACTED: MicroRNA-381 facilitates autophagy and apoptosis in prostate cancer cells via inhibiting the RELN-mediated PI3K/AKT/mTOR signaling pathway.

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Western blot results in Figures 5B+D, 6B+D, 7B+D, and 8C, which appear to have a similar phenotype as many other publications, as detailed here: https://pubpeer.com/publications/70795908CC4CEFC1753E19583700F4; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. In addition, a portion of Figure 6C, ‘miR-381 mimic’ group appeared to contain image similarities with Figure 6C, ‘si-RELN’ group. The journal requested that the corresponding author comment on these concerns and provide the raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article. Copyright © 2020 Elsevier Inc. All rights reserved.

Citation

Wenbiao Liao, Yi Zhang. RETRACTED: MicroRNA-381 facilitates autophagy and apoptosis in prostate cancer cells via inhibiting the RELN-mediated PI3K/AKT/mTOR signaling pathway. Life sciences. 2020 Aug 01;254:117672

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PMID: 32304760

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