Orbital non-HIV immune reconstitution inflammatory syndrome after cytapheresis.

The immune reconstitution inflammatory syndrome is a phenomenon typically described in HIV patient during the restoration of CD4 count after highly active antiretroviral therapy. Non-HIV immune reconstitution inflammatory syndrome has also been described after organ transplantation or immune recovery in neutropenic patients. We report the case of a 50-year-old man who presented to our department with left painful proptosis and ophthalmoplegia 2 days after having performed cytapheresis for a mantel cell lymphoma. Systemic work up and biopsy were performed and symptoms were relieved with intravenous steroids therapy. To our knowledge, this is the first case of orbital non-HIV immune reconstitution inflammatory syndrome described in the literature.

Citation

Jeremy Chiabo, Sacha Nahon-Esteve, Mohamed Alketbi, Sandra Lassalle, Nathalie Tieulie, Arnaud Martel. Orbital non-HIV immune reconstitution inflammatory syndrome after cytapheresis. European journal of ophthalmology. 2021 May;31(3):NP85-NP88

Mesh Tags

PMID: 32312094

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