Propranolol-resistant infantile hemangioma successfully treated with sirolimus.

Victoria L Dávila-Osorio, Helena Iznardo, Esther Roé, Lluis Puig, Eulalia Baselga

Pediatric dermatology 2020 Jul

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Infantile hemangiomas are the most common benign vascular tumors in childhood. Propranolol is the first-line treatment for infantile hemangiomas, but failures may occur. Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations and vascular tumors. We present the case of a child with multiple infantile hemangiomasthat was successfully treated with sirolimus and propranolol after failure of combined propranolol and prednisolone treatment. © 2020 Wiley Periodicals LLC.

Citation

Victoria L Dávila-Osorio, Helena Iznardo, Esther Roé, Lluis Puig, Eulalia Baselga. Propranolol-resistant infantile hemangioma successfully treated with sirolimus. Pediatric dermatology. 2020 Jul;37(4):684-686