Marharyta V Laktsevich-Iskryk, Anton S Rudovich, Vladimir N Zhabinskii, Vladimir A Khripach, Alaksiej L Hurski
Steroids 2020 JulA photochemical approach to 18-nor-17β-hydroxymethyl-17α-methylandrost-13-ene unit of the long-term metabolites of 17-methylated androgenic anabolic steroids (AAS) is reported. It is based on a visible light-promoted radical decarboxylative alkynylation of steroidal redox-active ester. The developed method was used in synthesis of the long-term metabolite of AAS oxymesterone. Copyright © 2020 Elsevier Inc. All rights reserved.
Marharyta V Laktsevich-Iskryk, Anton S Rudovich, Vladimir N Zhabinskii, Vladimir A Khripach, Alaksiej L Hurski. A photochemical approach to 18-nor-17β-hydroxymethyl-17α-methylandrost-13-ene steroids. Steroids. 2020 Jul;159:108652
PMID: 32360417
View Full Text