Correlation Engine 2.0
Clear Search sequence regions

  • alleles (1)
  • antigens (2)
  • bolivia (2)
  • DRB1 (2)
  • easter island (2)
  • ethnic group (1)
  • gene (3)
  • HLA (7)
  • humans (1)
  • Inca (1)
  • indians south american (1)
  • peru (1)
  • volunteers (1)
  • Sizes of these terms reflect their relevance to your search.

    Quechua Amerindians established Inca Empire and chose Cuzco as their capital. Their language is closely related to that of Aymara ethnic group and both of them were originated from Titikaka Lake Altiplano area. In the present study we have analyzed Bolivian Quechua HLA profile and found that it has common characters with other Andean and Pacific Amerindians (Uros, Aymaras, Lamas, Mapuches, Athabascan), and Pacific Islanders, including Easter Islanders: relatively high frequency of HLA-A*24 (:02), class II haplotypes DRB1*08:02-DQB1*04:02, and DRB1*04:03-DQB1* 03:02. Titikaka Lake area prehistoric populations: Quechua, Aymaras and Uros are closely related according to HLA Nei DA genetic distances and other HLA traits: they built up Tiwanaku culture, which resembles that of Easter Island (i.e.: similar giant heads); later, Quechuas also moved to Cuzco. This genetic reletedness together with Easter Island and Titikaka Lake Tiwanaku (Bolivia, Peru) cultural common similarities support a prehistoric Pacific people/Amerindians gene flow. Copyright © 2020 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.


    Antonio Arnaiz-Villena, Ignacio Juarez, Adrian Lopez-Nares, Estefania Crespo-Yuste, Alvaro Callado, Fabio Suarez-Trujillo. HLA study in Bolivian Quechua Amerindians from Titikaka Lake Area. Human immunology. 2020 Jul;81(7):321-322

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 32418640

    View Full Text