Effects of pupil size on canine visual evoked potential with pattern stimulation.

Seiya Maehara, Yoshiki Itoh, Wataru Kurimoto, Yasunari Kitamura, Yosuke Ito, Miri Hayashi, Arisa Masuko

The Journal of veterinary medical science 2020 Jul 10

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The purpose of this study was to investigate the effects of pupil diameter on canine visual evoked potentials with pattern stimulation (P-VEP). Atropine eye drop (1.0%) was applied to both eyes as a cycloplegic drug, and tafluprost eye drop (0.015%) was applied to one eye that was selected randomly for miosis (miosis group). The other eye did not receive tafluprost (mydriasis group). P-VEP was recorded at three pattern sizes. The P100 implicit time at a small pattern size in the mydriasis group was significantly prolonged compared to the miosis group. We hypothesized that the prolonged P100 implicit time under mydriatic conditions was due to increased spherical aberrations and concluded that mydriatic conditions affected P100 implicit time in canine P-VEP recordings.

Citation

Seiya Maehara, Yoshiki Itoh, Wataru Kurimoto, Yasunari Kitamura, Yosuke Ito, Miri Hayashi, Arisa Masuko. Effects of pupil size on canine visual evoked potential with pattern stimulation. The Journal of veterinary medical science. 2020 Jul 10;82(7):922-925