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Haemoptysis is a major complication of cystic fibrosis (CF) and is associated with pulmonary exacerbations and admission to the hospital. The US CF Pulmonary Foundation guidelines fail to reach consensus on haemoptysis treatment regarding pharmacotherapy options. We describe a case in which systemic tranexamic acid was utilized to treat haemoptysis in a CF adult patient who was experiencing progressively worsening haemoptysis despite numerous bronchial artery embolization procedures. The use of antifibrinolytic agents may be of potential benefit in refractory haemoptysis episodes in adult CF patients. © 2020 John Wiley & Sons Ltd.

Citation

Elizabeth Gavioli, Cho Cho Aung. Haemoptysis management in cystic fibrosis: A case report and treatment pathway. Journal of clinical pharmacy and therapeutics. 2020 Aug;45(4):845-847

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PMID: 32479647

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