In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD+ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD+ precursor niacin, identifying NAD+ boosting as a potential treatment for this devastating disease. Copyright © 2020 Elsevier Inc. All rights reserved.
Eduardo Nunes Chini. Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients. Cell metabolism. 2020 Jun 02;31(6):1041-1043
PMID: 32492387
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