Molecular basis of macrolide-lincosamide-streptogramin (MLS) resistance in Finegoldia magna clinical isolates.

François Guérin, Sabrine Lachaal, Michel Auzou, Cécile Le Brun, Olivier Barraud, Jean-Winoc Decousser, Reto Lienhard, Régine Baraduc, Luc Dubreuil, Vincent Cattoir

Anaerobe 2020 Aug

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Of 69 clinical isolates of Finegoldia magna tested, 36% presented high-level MICs of erythromycin (>256 μg/ml), harboring erm(A) (n = 20) or erm(B) (n=5). Of nine isolates exhibiting an inducible resistance phenotype to macrolides-lincosamides-streptogramins B, four (44%) were susceptible with a potential risk of treatment failure due to emergence of resistant mutants. Copyright © 2020 Elsevier Ltd. All rights reserved.

Citation

François Guérin, Sabrine Lachaal, Michel Auzou, Cécile Le Brun, Olivier Barraud, Jean-Winoc Decousser, Reto Lienhard, Régine Baraduc, Luc Dubreuil, Vincent Cattoir. Molecular basis of macrolide-lincosamide-streptogramin (MLS) resistance in Finegoldia magna clinical isolates. Anaerobe. 2020 Aug;64:102220