Management of Barrett's esophagus with dysplasia refractory to radiofrequency ablation.

Kara L Raphael, Arvind J Trindade

World journal of gastroenterology 2020 May 07

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Radiofrequency ablation (RFA) is very effective for eradication of flat Barrett's mucosa in dysplastic Barrett's esophagus after endoscopic resection of raised lesions. However, in a minority of the time, RFA may be ineffective at eradication of the Barrett's mucosa. Achieving complete eradication of intestinal metaplasia can be challenging in these patients. This review article focuses on the management of patients with dysplastic Barrett's esophagus refractory to RFA therapy. Management strategies discussed in this review include optimizing the RFA procedure, optimizing acid suppression (with medical, endoscopic, and surgical management), cryotherapy, hybrid argon plasma coagulation, and EndoRotor resection. ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

Citation

Kara L Raphael, Arvind J Trindade. Management of Barrett's esophagus with dysplasia refractory to radiofrequency ablation. World journal of gastroenterology. 2020 May 07;26(17):2030-2039