Genetic biomarkers: Potential roles in cancer diagnosis.

Rozhgar A Khailany, Sherwan Ahmed Aziz, Suhel Mawlood Najjar, Muhammad Safdar, Mehmet Ozaslan

Cellular and molecular biology (Noisy-le-Grand, France) 2020 Jun 05

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Biomarkers are indicators of pathogenic processes, typical biological processes, or pharmacological reactions to a therapy. It has several potential usages in cancer; differential diagnosis, prognosis, risk assessment, therapeutic response, and monitoring of disease progression. Recently, advances in oncomarkers raised significant opportunities for enhancing management of cancer. Chromosomal aberration, molecular impairment and epigenetic alteration might be applied to diagnose and prognose cancer and its epidemiology. Some oncomarkers are specific and highly sensitive for detection. An oncomarker might be used to see how the body reacts to an intervention or a situation. The present study represents a short review about various genetic oncomarkers with diagnostic and prognostic values.

Citation

Rozhgar A Khailany, Sherwan Ahmed Aziz, Suhel Mawlood Najjar, Muhammad Safdar, Mehmet Ozaslan. Genetic biomarkers: Potential roles in cancer diagnosis. Cellular and molecular biology (Noisy-le-Grand, France). 2020 Jun 05;66(3):1-7