Correlation Engine 2.0
Clear Search sequence regions

  • control group (2)
  • cortisol (1)
  • humans (3)
  • saliva (1)
  • skin (4)
  • wound (3)
  • Sizes of these terms reflect their relevance to your search.

    This study investigated whether environmental enrichment (EE) could reduce stress and improve wound healing in humans. 120 participants underwent a standardised tape-stripping procedure and were then randomised to interact for 30 minutes with one of three EE interventions (comfort blankets as tactile enrichment, music as auditory enrichment or a Paro robot as multi-sensory enrichment) or to a control group. Skin barrier recovery (SBR) was measured using transepidermal water loss at baseline, after tape-stripping and after the intervention. Psychological variables, cortisol and alpha-amylase were measured at the three time-points. SBR did not significantly differ between the EE conditions and the control condition. The music condition had higher stimulation levels than the control condition, and the comfort condition had significantly lower relaxation levels than the control condition after the intervention. The EE interventions tested were not beneficial for wound healing compared to a control group. Limitations were that the sample were not stressed and an active control condition was used.


    Mikaela Law, Paul Jarrett, Urs M Nater, Nadine Skoluda, Elizabeth Broadbent. The effects of environmental enrichment on skin barrier recovery in humans: a randomised trial. Scientific reports. 2020 Jun 17;10(1):9829

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 32555211

    View Full Text