Application of Gellan Gum-Based Scaffold for Regenerative Medicine.

Gellan gum (GG) is a linear microbial exopolysaccharide which is derived naturally by the fermentation process of Pseudomonas elodea. Application of GG in tissue engineering and regeneration medicine (TERM) is already over 10 years and has shown great potential. Although this biomaterial has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations, a variety of modification methods have been suggested due to some disadvantages such as mechanical properties, high gelation temperature, and lack of attachment sites. In this review, the application of GG-based scaffold for tissue engineering and approaches to improve GG properties are discussed. Furthermore, a recent trend and future perspective of GG-based scaffold are highlighted.

Citation

Joo Hee Choi, Wonchan Lee, Cheolui Song, Byung Kwan Moon, Sun-Jung Yoon, Nuno M Neves, Rui L Reis, Gilson Khang. Application of Gellan Gum-Based Scaffold for Regenerative Medicine. Advances in experimental medicine and biology. 2020;1249:15-37

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PMID: 32602088

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