Multimodality Imaging Features of a Misleading Sacral Giant Cell Tumor in 18F-FDG PET/CT, Bone Scan, and MRI.

Sebastien Dejust, Pascaline Jallerat, Pauline Soibinet-Oudot, Christelle Jouannaud, David Morland

Clinical nuclear medicine 2020 Oct

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We report the case of an asymptomatic 66-year-old woman referred for initial staging of an invasive ductal breast carcinoma. Initial workup incidentally revealed a bone tumor of right sacral wing corresponding to a giant cell tumor (GCT). We present the imaging characteristics of GCT on Tc-HDP bone scan (doughnut sign), F-FDG PET/CT (intense and heterogeneous uptake of a prominent geographic lytic lesion with partial rupture of cortical), and MRI (hyposignal with gadolinium enhancement on T1-weighted images and heterogeneous hypersignal on T2-weighted images). GCT is a benign but locally aggressive primary bone tumor, constituting a pitfall and diagnostic challenge.

Citation

Sebastien Dejust, Pascaline Jallerat, Pauline Soibinet-Oudot, Christelle Jouannaud, David Morland. Multimodality Imaging Features of a Misleading Sacral Giant Cell Tumor in 18F-FDG PET/CT, Bone Scan, and MRI. Clinical nuclear medicine. 2020 Oct;45(10):800-801