Clostridium difficile disease in solid organ transplant recipients: a recommended treatment paradigm.

Darren Wong, Neha Nanda

Current opinion in organ transplantation 2020 Aug

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Organ transplant recipients have an increased incidence of Clostridium difficile disease and lower clinical response rates compared with the general population. Transplant specific treatment approaches are not defined. Therefore, a review of therapeutics in the transplant population is needed. A literature review on the current therapies for C. difficile was performed focusing on the evidence in transplant recipients and immunosuppressed populations. Transplant patients warrant an aggressive approach to treatment. The authors propose a suggested treatment paradigm for therapy.

Citation

Darren Wong, Neha Nanda. Clostridium difficile disease in solid organ transplant recipients: a recommended treatment paradigm. Current opinion in organ transplantation. 2020 Aug;25(4):357-363