Lipid droplets (LDs) are neutral lipid storage organelles assembled at the endoplasmic reticulum (ER). A new study reveals that the high membrane curvature of ER tubules catalyzes the nucleation of a neutral lipid lens, an early step in LD biogenesis. Copyright © 2020 Elsevier Inc. All rights reserved.
Melissa A Roberts, Ashley Segura-Roman, James A Olzmann. Organelle Biogenesis: ER Shape Influences Lipid Droplet Nucleation. Current biology : CB. 2020 Jul 06;30(13):R770-R773
PMID: 32634419
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