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Ploidy Leads a Molecular Motor to Walk Different Paths to Drug Resistance.

Alexander M Real, William M Marsiglia, Arvin C Dar

Cell chemical biology 2020 Jul 16


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    In this issue of Cell Chemical Biology, Pisa et al. (2020) find that haploid and diploid cells differentially develop resistance to the CENP-E inhibitor GSK923295. The results highlight the power of tumor cells to evade growth inhibition and potentially inform the design of next-generation CENP-E drugs to overcome resistance. Copyright © 2020 Elsevier Ltd. All rights reserved.

    Citation

    Alexander M Real, William M Marsiglia, Arvin C Dar. Ploidy Leads a Molecular Motor to Walk Different Paths to Drug Resistance. Cell chemical biology. 2020 Jul 16;27(7):770-772

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    PMID: 32679092

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