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Necroptosis is a cell death pathway involved in inflammation and disease. In this issue, Ko et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201912047) link SARM1, the executioner of Wallerian degeneration of axons, to necroptosis, revealing a unique form of axonal disassembly likely involved in neurodegenerative disorders. © 2020 Pierchala.
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Brian A Pierchala. Necroptosis is SARMful to your health. The Journal of cell biology. 2020 Aug 03;219(8)
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PMID: 32697820
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