Influence of immunosuppression on seroconversion against SARS-CoV-2 in two kidney transplant recipients.

Solid organ transplant recipients are at risk for infectious complications due to chronic immunosuppression. The outbreak of coronavirus disease 2019 (COVID-19) in the United States has raised growing concerns for the transplant patient population. We seek to add to the current limited literature on COVID-19 in transplant recipients by describing the clinical course of two kidney transplant recipients with SARS-CoV-2 infection monitored by both RT-PCR and serology. Through careful adjustment of their immunosuppression regimen, both patients had excellent recovery with intact graft function and development of anti-SARS-CoV-2 antibodies. © 2020 Wiley Periodicals LLC.

Citation

Aileen X Wang, Orlando Quintero Cardona, Dora Y Ho, Stephan Busque, Colin R Lenihan. Influence of immunosuppression on seroconversion against SARS-CoV-2 in two kidney transplant recipients. Transplant infectious disease : an official journal of the Transplantation Society. 2021 Feb;23(1):e13423

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PMID: 32701196

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