Atypical optic neuritis: the importance of a comprehensive diagnostic work-up].

R Yaïci, A Carzoli, F Bétis, G Geerling, R Guthoff, T Guthoff

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2021 Jun

filter terms:

A 65-year-old woman was referred for sudden bilateral loss of vision. She was vaccinated a few days earlier. The ophthalmological examination showed a massive optic disc swelling on both eyes. Magnetic resonance imaging (MRI) revealed suspected bilateral optic neuritis without cerebral involvement or transverse myelitis. After serological detection of anti-MOG (myelin oligodendrocyte glycoprotein) antibodies, the patient was treated with high-dose corticosteroid pulse therapy until vision recovered. Discussion: an atypical optic neuritis may indicate a neuromyelitis optica spectrum disorder (NMOSD), which should be further characterized by determination of Aquaporin 4(AQP4)-IgG and MOG-IgG.

Citation

R Yaïci, A Carzoli, F Bétis, G Geerling, R Guthoff, T Guthoff. Atypical optic neuritis: the importance of a comprehensive diagnostic work-up]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 2021 Jun;118(6):593-596