Disseminated fusariosis in a patient with bone marrow aplasia.

Danielle Ferreira Chagas, Lucia Martins Diniz, Elton Almeida Lucas, Paulo Sergio Emerich Nogueira

Anais brasileiros de dermatologia 2020 Sep - Oct

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Fusariosis is a superficial or systemic infection, which occurs mainly in immunocompromised hosts, especially in patients with hematological neoplasia; 70%-75% of the cases present cutaneous manifestations. The disseminated form is rare and difficult to diagnose; even with specific treatment, the evolution is usually fatal. Currently, it is considered an emerging disease; in some centers, it is the second most common cause of invasive mycosis, after aspergillosis. The authors describe a case of a female patient with idiopathic bone marrow aplasia and disseminated fusariosis, who initially appeared to benefit from voriconazole and amphotericin B; however, due to persistent neutropenia, her clinical condition deteriorated with fatal evolution. Copyright © 2020 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.

Citation

Danielle Ferreira Chagas, Lucia Martins Diniz, Elton Almeida Lucas, Paulo Sergio Emerich Nogueira. Disseminated fusariosis in a patient with bone marrow aplasia. Anais brasileiros de dermatologia. 2020 Sep - Oct;95(5):609-614