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Two new steroid sulfates from a cheilostome bryozoan, Calyptotheca sp.

Sona Rani Roy, Alisa Minei, Peni Ahmadi, Idam Hermawan, Viqqi Kurnianda, Matthew H Dick, Junichi Tanaka

Natural product research 2022 Feb


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    Two new steroid sulfates 1 and 2 were obtained from a lipophilic extract of an undescribed bryozoan species in the genus Calyptotheca. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and chemical modifications. Steroids 1 and 2 exhibited moderate cytotoxicity at IC50 54 and 30 µM, respectively, against NBT-T2 cells.

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    Sona Rani Roy, Alisa Minei, Peni Ahmadi, Idam Hermawan, Viqqi Kurnianda, Matthew H Dick, Junichi Tanaka. Two new steroid sulfates from a cheilostome bryozoan, Calyptotheca sp. Natural product research. 2022 Feb;36(3):742-747

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    PMID: 32755232

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