Noncanonical Amino Acids in Synthetic Biosafety and Post-translational Modification Studies.

The incorporation of noncanonical amino acids (ncAAs) has been extensively studied because of its broad applicability. In the past decades, various in vitro and in vivo ncAA incorporation approaches have been developed to generate synthetic recombinant proteins. Herein, we discuss the methodologies for ncAA incorporation, and their use in diverse research areas, such as in synthetic biosafety and for studies of post-translational modifications. © 2020 Wiley-VCH GmbH.

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Donghyeok Gang, Hee-Sung Park. Noncanonical Amino Acids in Synthetic Biosafety and Post-translational Modification Studies. Chembiochem : a European journal of chemical biology. 2021 Feb 02;22(3):460-468

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PMID: 32794239

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